
Transcranial photobiomodulation (tPBM) is a non‑invasive therapeutic modality that uses near‑infrared (NIR) light to modulate brain cellular metabolism, reduce neuro‑inflammation, support neurogenesis and synaptic repairPubMed. This article introduces an advanced multi‑zone PBM helmet equipped with dual‑wavelength 810 nm visible near‑infrared and 1070 nm invisible near‑infrared LED arrays. The helmet provides independent regional stimulation across frontal, parietal, occipital and temporal brain lobes, supporting both continuous‑wave (CW) and pulsed‑wave (PW) modes with adjustable power, frequency (1‑20000 Hz), and session duration (1‑60 minutes). We review its biological mechanisms, target clinical indications, device operation protocols, safety considerations, and cite peer‑reviewed literature for brain photobiomodulation. **Disclaimer**: This article is for educational purposes only. It is not medical advice. Always consult your healthcare provider before starting any new light‑therapy protocol.